Nutrient Needs in Perimenopause and Beyond
Share
As women enter midlife, hormonal shifts influence multiple interconnected physiological systems affecting bone health, cardiovascular function, metabolic regulation, and maintaining a healthy inflammatory response. Even with a nutrient-dense diet, research shows that many women begin to experience shortfalls in key micronutrients needed to sustain these pathways.
That’s why we created The Pause Nutrition MenoMulti, a multi-layered daily formula (available for purchase on December 11, 2025) designed to address areas where nutrient needs commonly change during midlife. Our goal was simple: to combine trusted, clinically studied ingredients that may help support cardiovascular and metabolic health, and overall well-being during perimenopause and beyond.*
Studies in midlife women highlight specific vitamins and minerals that play protective roles during hormone-related shifts particularly in systems such as the heart, brain, and bones. MenoMulti brings these components together in one daily supplement to help close nutrient gaps and support the body through this transition and beyond.*
A Multi-Layered Approach to Midlife Health
Each layer of the formula targets a distinct area of support that becomes more vulnerable as hormones, metabolism, and cellular function evolve with age.
Cardiovascular Support
Shifting estrogen levels can influence lipid metabolism, blood pressure, and insulin sensitivity, all of which affect cardiovascular health. Nutrients that support endothelial function and mitochondrial efficiency may help promote healthy circulation and metabolic stability.*
A Healthy Inflammatory Response
Inflammaging refers to the gradual rise in low-grade inflammation that often accompanies midlife. This persistent inflammatory state can affect joint comfort, and metabolic health.1 Nutrients that strengthen our defenses and lend to a healthy inflammatory response may support better balance during this inflammaging process.*
Cellular Energy Metabolism
Mitochondria power cellular energy production.2 As estrogen declines, mitochondrial efficiency may decrease, contributing to fatigue, reduced exercise tolerance, brain fog, and metabolic slowing.1,3 Targeted nutrients that support mitochondrial activity and energy production help maintain resilience through these shifts.*
The Power of a Focused Daily Formula
Thriving through midlife requires a strategic, multi-layered approach. Nutrition, movement, sleep, and stress management work together to support balance during this stage of life. A foundation of nutrient-dense foods, rich in protein, colorful plants, and healthy fats, paired with resistance training and blood-sugar stability helps support strength, cognition, and metabolic health.
Yet even with these habits, midlife transitions can create specific nutrient deficits that diet alone may not fully address. That’s where targeted supplementation can help. Choosing a daily formula designed for your body’s current physiology adds another layer of support, helping to close gaps, sustain energy, and keep interconnected systems functioning in harmony.
The Science Behind the Formula
The Pause Nutrition MenoMulti combines clinically researched nutrients selected for their complementary roles across multiple systems:
- geniVida® Genistein: a plant-based isoflavone shown to support bone density and vascular health,4 insulin sensitivity5 and to help regulate inflammatory pathways through selective estrogen receptor modulation.6* We selected geniVida because it’s a patented, non-soy pure genistein product produced in Switzerland which offers a pure and clean ingredient backed by clinical studies.
- Bioactive B-Vitamins: methylated and coenzyme forms that fuel cellular metabolism, support methylation, and help maintain healthy homocysteine levels, a biomarker of cardiovascular function.7*
- Coenzyme Q10 (CoQ10): a key mitochondrial cofactor that supports cellular energy production, helping to reduce fatigue and oxidative stress.8, 9*
- Biotin: an essential coenzyme involved in protein synthesis, energy metabolism, and keratin structure for healthy hair, skin, and nails.10, 11, 12*
Together, these ingredients form a multi-layered network of support for systems most impacted during midlife transitions, helping women maintain balance, vitality, and long-term well-being.*
The Rigorous Standards The Pause Nutrition Is Known For
As with every product Dr. Mary Claire Haver stands behind, The Pause Nutrition MenoMulti is formulated with high-quality, clinically researched ingredients, manufactured in GMP-certified facilities, gluten-free, and third-party tested for purity and potency.
Before Taking Any New Supplement
Every woman’s health profile is unique. If you are pregnant, nursing, allergic, have a medical condition, take medications (including anticoagulants/antiplatelets such as warfarin, blood-pressure or thyroid medications), or have pending lab tests (due to biotin’s potential lab-test interference), consult with your clinician before using this or any dietary supplement.
