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E150
July 28, 2026
Menopause Masterclass: How to Read Your Labs
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In this episode of unPAUSED, Dr. Mary Claire Haver delivers a solo masterclass on the lab work every woman in perimenopause, menopause, and post menopause should understand and request from her doctor. Dr. Haver explains why standard annual labs, built for a general population, routinely miss the specific hormonal, metabolic, cardiovascular, and bone related changes that happen during the menopause transition, and she walks through seven categories of testing that give a far more complete picture of a woman's health.

She starts with an advanced lipid panel, explaining why LDL alone is not enough and why ApoB, Lp(a), and small dense LDL particles matter for women whose cardiovascular risk shifts as estrogen declines. She covers fasting glucose and fasting insulin together, showing how the HOMA IR score can reveal insulin resistance long before a diabetes diagnosis. She addresses bone health in depth, arguing that waiting until age 65 for a baseline DEXA scan is far too late given how much bone density can be lost in the years surrounding menopause, and she details safe vitamin D supplementation ranges and optimal target levels.

Dr. Haver also explains why thyroid dysfunction so closely mimics perimenopause symptoms and why TSH alone can miss the full picture, why ferritin testing catches iron depletion long before anemia develops, and how heavy or irregular bleeding in perimenopause contributes to that iron loss. She discusses when and why to check estradiol and testosterone levels, and why one time hormone tests are not reliable for diagnosing perimenopause itself. The seventh lab category is high sensitivity C reactive protein, a marker of chronic inflammation tied to declining estrogen.

The second half of the episode is devoted to twelve common ways women feel dismissed by their doctors, from being told they are too young for perimenopause to being offered an antidepressant without any hormonal discussion. For each scenario, Dr. Haver gives specific language women can use to advocate for themselves, along with pointers to the Menopause Society guidelines, the validated Menopause Quiz, and a clinician directory available at thepauselife.com. She ends with a personal reflection on her own post menopausal life, encouraging listeners to seek out informed care rather than accept dismissal as the final word.

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Chapters

00:00:00 – Why Standard Bloodwork Misses Menopause
00:04:12 – Advanced Cholesterol Tests Every Woman Needs
00:09:04 – Hidden Insulin Resistance & Blood Sugar
00:13:29 – Bone Density & Vitamin D Before It's Too Late
00:23:07 – Thyroid Tests That Mimic Menopause
00:24:44 – Iron Deficiency & Heavy Periods
00:29:10 – When Hormone Testing Actually Helps
00:32:10 – The Inflammation Test to Ask For
00:39:20 – How to Advocate for Yourself at the Doctor
00:41:35 – "You're Too Young for Perimenopause"
00:43:26 – Birth Control vs. Hormone Therapy
00:44:31 – When Your Doctor Says Hormones Are Too Risky
00:47:14 – Why "Normal" Symptoms Still Deserve Treatment
00:49:22 – Weight Gain Isn't Just Calories
00:53:08 – The New Perimenopause & Final Takeaways
00:55:12 – Finding a Menopause-Informed Doctor
00:56:07 – Why Life Can Get Better After Menopause

About the guest

Dr. Mary Claire Haver

Dr. Mary Claire Haver, MD, FACOG, MSCP, is a board-certified OB-GYN and Menopause Society Certified Practitioner. She is the #1 New York Times bestselling author of The New Menopause, a book written to empower women with evidence-based menopause care, and the newly released New York Times Bestseller, The New Perimenopause: An Evidence-Based Guide to Surviving the Zone of Chaos and Feeling Like Yourself Again. She earned her medical degree from Louisiana State University Medical Center and completed her residency in Obstetrics and Gynecology at the University of Texas Medical Branch (UTMB), where she is now an Adjunct Associate Professor. 

In 2021, she founded The ‘Pause Wellness, a clinic committed to providing comprehensive menopause care. In 2023, she launched ThePauseLife.com, a trusted resource for women navigating menopause. She is also the host of the podcast unPAUSED with Dr. Mary Claire Haver, where she continues the conversation on women’s health, empowerment, and evidence-based care. 

A sought-after speaker and educator, Dr. Haver is a regular contributor to national media and has been featured in The New York Times Forbes The Today Show CBS Mornings , and Oprah’s Menopause Revolution, and the 2025 TIME100 Creators List . Her social media presence has grown to more than 7 million followers, where she continues to demystify menopause with relatable, science-backed content.